The Lesotho HIV Strategic Plan 2023-2028 outlines a comprehensive approach to address key challenges and accelerate progress in preventing new HIV infections, eMTCT, integrating health services, promoting behavior change, upholding human rights, achieving gender equality, strengthening community systems, ensuring health and social protection, securing HIV health products and technologies, improving human resources for health, leveraging data science and innovation, sustaining financing, addressing emergencies and disasters, and enhancing leadership, advocacy, and coordination.