This report provides insights into the progress made in implementing HIV interventions in the Global Fund supported countries. It highlights the increased investments in HIV prevention from US$705 million over the 2018-2020 period to more than US$870 million over the 2021-2023 period. The investments in HIV prevention over this period are focused on the urgent need to close gaps in access to the interventions in the prevention toolkit including pre-exposure prophylaxis, post-exposure prophylaxis, condoms and lubricants, harm reduction programmes for key and priority populations.