This report focusses on challenging the stigma and discrimination experienced by individuals who engage in chemsex, in order that they can equitably enjoy the full range of human rights afforded to all people. As with all of INPUD’s community-driven documents, it discusses and documents the human rights, health, wellbeing, and lived realities and experiences of people who use drugs, in this case, people who engage in chemsex. As INPUD’s first document focussing on this community, it draws illustratively from a chemsex consultation undertaken in South Africa by INPUD.