July 2016 This document puts forward a framework with new strategic directions for 2016–2021 on voluntary medical male circumcision (VMMC) for HIV prevention as the follow-on to the Joint Strategic Action Framework 2012–2016 (1). The new directions focus on adolescent boys and men, and take into account a range of physical and psychosocial health issues. They highlight the need for innovative approaches to overcome current barriers to services, increase acceptability, and address inequalities in access and coverage.