These national guidelines on managing HIV and AIDS, revised based on evidence and recommendations that have emerged since the sixth edition, aim to sustain the achievements of Tanzania's programme and fast-track progress towards national and global targets. The guidelines cover adult, adolescent, and pediatric HIV and AIDS management, including nutrition, mental health, management of opportunistic infections, community-based HIV services and the continuum of care, counseling for HIV testing, management of advanced HIV disease and ART adherence and disclosure.