This plan’s purpose is to guide HIV programming, resource allocation and implementation of the HIV response in Zimbabwe from 2021 to 2025 and to accelerate the transition to a sustainable phase. The plan includes programmes and strategies for combination HIV prevention; integration of the HIV response with sexually transmitted infection prevention and management, noncommunicable diseases, and mother and child nutrition programmes; programmes for vulnerable and key populations; steps to strengthen social enablers; and activities to strengthen health and community systems.