Access to PrEP is still highly concentrated in a small number of countries; even within countries with widespread PrEP access, inequalities have emerged. The Global Men and HIV Technical Working Group’s (MENHT’s) first webinar on men and pre-exposure prophylaxis (PrEP) will include a presentation on the World Health Organization’s updated guidelines on PrEP and reports on efforts to improve men’s access to and effective use of PrEP in Guatemala, the Philippines, South Africa and Zambia.