This case study highlights Uganda’s unique strategy to integrate HIV prevention into multi-sector budgeting. All state-owned enterprises and public corporations must allocate at least 0.1% of their budget (excluding certain expenses) to HIV/AIDS intervention in response to a presidential directive issued in 2018. By 2023, domestic financing for HIV prevention had increased with an additional USD 16 million mobilized for HIV prevention. The Uganda AIDS Commission oversees the resource allocation and use.